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PFAM:PF01847 (5 hits)
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Modifier evidence source
Curated
inferred
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Index
Egl nine homolog 1
Motif
Protein
Start
End
Switch Type
Switch Subtype
Switch description
Information
Evidence
Egl nine homolog 1 -
EGLN1
-
Homo sapiens
DEG_ODPH_VHL_1
HIF1A_HUMAN
400
413
Binary
Physicochemical compatibility
Hydroxylation of P402 in the VHL-binding motif of
Hypoxia-inducible factor 1-alpha (HIF1A)
induces binding to the
Von Hippel-Lindau disease tumor suppressor (VHL)
protein.
details
Curated
DEG_ODPH_VHL_1
HIF1A_HUMAN
562
574
Binary
Physicochemical compatibility
Hydroxylation of P564 in the VHL-binding motif of
Hypoxia-inducible factor 1-alpha (HIF1A)
induces binding to the
Von Hippel-Lindau disease tumor suppressor (VHL)
protein.
details
Curated
DEG_ODPH_VHL_1
EPAS1_HUMAN
403
416
Binary
Physicochemical compatibility
Hydroxylation of P405 in the VHL-binding motif of
Endothelial PAS domain-containing protein 1 (EPAS1)
induces binding to the
Von Hippel-Lindau disease tumor suppressor (VHL)
protein.
details
Curated
DEG_ODPH_VHL_1
EPAS1_HUMAN
529
542
Binary
Physicochemical compatibility
Hydroxylation of P531 in the VHL-binding motif of
Endothelial PAS domain-containing protein 1 (EPAS1)
induces binding to the
Von Hippel-Lindau disease tumor suppressor (VHL)
protein.
details
Curated
DEG_ODPH_VHL_1
HIF3A_HUMAN
490
502
Binary
Physicochemical compatibility
Hydroxylation of P492 in the VHL-binding motif of
Hypoxia-inducible factor 3-alpha (HIF3A)
induces binding to the
Von Hippel-Lindau disease tumor suppressor (VHL)
protein.
details
Curated
