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| Motif | Protein | Start | End | Switch Type | Switch Subtype | Switch description | Information | Evidence |
Cyclin-dependent kinase 5 - CDK5 - Mus musculus | ||||||||
| TRG_AP2beta_CARGO_2 | PI51C_MOUSE | 633 | 644 | Binary | Physicochemical compatibility | Phosphorylation of S645 in Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (Pip5k1c) impedes binding to AP-2 complex subunit beta (Ap2b1), while dephosphorylation by calcineurin promotes binding. These phosphorylation and dephosphorylation events are important for the regulation of clathrin coat formation associated with synaptic vesicles. | Curated | |