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Group by :Switch typeMotif classProteinEnzymePathway         Hide inferred   Group Index    Colouring Info              Filtered: PFAM:PF09066 (1 hits) x


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Cyclin-dependent kinase 5 (Mus)


MotifProteinStartEndSwitch TypeSwitch SubtypeSwitch descriptionInformationEvidence

Cyclin-dependent kinase 5 - CDK5 -  Mus musculus
TRG_AP2beta_CARGO_2 PI51C_MOUSE633644BinaryPhysicochemical compatibilityPhosphorylation of S645 in Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (Pip5k1c) impedes binding to AP-2 complex subunit beta (Ap2b1), while dephosphorylation by calcineurin promotes binding. These phosphorylation and dephosphorylation events are important for the regulation of clathrin coat formation associated with synaptic vesicles.
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Curated
           
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