switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Hide inferred Group Index Colouring Info Filtered: UNIPROT:P04626 (9 hits) x

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Curated inferred

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Receptor tyrosine-protein kinase erbB-2

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Protein

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Evidence

Receptor tyrosine-protein kinase erbB-2 - ERBB2 - Homo sapiens
LIG_SH2_IC	ERBB2_HUMAN	1135	1144	Binary	Physicochemical compatibility	Phosphorylation of Y1139 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-2 (ERBB2) induces binding to the Growth factor receptor-bound protein 7 (GRB7) protein.	details	Inferred
LIG_SH2_IC	ERBB2_HUMAN	1135	1144	Binary	Physicochemical compatibility	Phosphorylation of Y1139 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-2 (ERBB2) induces binding to the Growth factor receptor-bound protein 7 (GRB7) protein.	details	Inferred
LIG_SH2_IE	ERBB2_HUMAN	1015	1031	Binary	Physicochemical compatibility	Phosphorylation of Y1023 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-2 (ERBB2) induces binding to the Tyrosine-protein kinase JAK1 (JAK1) protein.	details	Inferred
LIG_SH2_IE	ERBB2_HUMAN	1015	1031	Binary	Physicochemical compatibility	Phosphorylation of Y1023 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-2 (ERBB2) induces binding to the Tyrosine-protein kinase JAK2 (JAK2) protein.	details	Inferred
LIG_SH2_ID	ERBB2_HUMAN	1131	1147	Binary	Physicochemical compatibility	Phosphorylation of Y1139 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-2 (ERBB2) induces binding to the Breast cancer anti-estrogen resistance protein 3 (BCAR3) protein.	details	Inferred
LIG_SH2_ID	ERBB2_HUMAN	1131	1147	Binary	Physicochemical compatibility	Phosphorylation of Y1139 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-2 (ERBB2) induces binding to the Breast cancer anti-estrogen resistance protein 3 (BCAR3) protein.	details	Inferred
LIG_SH2_ID	ERBB2_HUMAN	1015	1031	Binary	Physicochemical compatibility	Phosphorylation of Y1023 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-2 (ERBB2) induces binding to the SH2 domain-containing protein 3A (SH2D3A) protein.	details	Inferred
LIG_SH2_III	ERBB2_HUMAN	1131	1147	Binary	Physicochemical compatibility	Phosphorylation of Y1139 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-2 (ERBB2) induces binding to the Signal transducer and activator of transcription 6 (STAT6) protein.	details	Inferred
LIG_SH2_III	ERBB2_HUMAN	1131	1147	Binary	Physicochemical compatibility	Phosphorylation of Y1139 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-2 (ERBB2) induces binding to the Signal transducer and activator of transcription 6 (STAT6) protein.	details	Inferred