Domain hiding |   Altered binding specificity |   Motif hiding |   Composite binding site formation |
  Uncategorised |   Rheostatic |   Allostery |   Avidity-sensing |
  Physicochemical compatibility |   Pre-translational |   Competition |
Protein | Start | End | Switch Type | Switch Subtype | Switch Description | Information |
LIG_EVH1_1 - Proline-rich motif binding to signal transduction class I EVH1 domains. | |||||||
XIRP1_HUMAN | 22 | 26 | Binary | Pre‑translational | Alternative splicing removes the EVH1-binding motif of Xin actin-binding repeat-containing protein 1 (XIRP1), abrogating binding to Protein enabled homolog (ENAH). | ||
XIRP1_HUMAN | 22 | 26 | Binary | Pre‑translational | Alternative splicing removes the EVH1-binding motif of Xin actin-binding repeat-containing protein 1 (XIRP1), abrogating binding to Vasodilator-stimulated phosphoprotein (VASP). | ||
LIG_EVH1_2 - Proline-rich motif binding to signal transduction class II EVH1 domains. | |||||||
GRM1_RAT | 1152 | 1156 | Binary | Pre‑translational | Alternative splicing removes the EVH1-binding motif of Metabotropic glutamate receptor 1 (Grm1), abrogating binding to Homer protein homolog 1 (Homer1), which is important for spatial targeting of Grm1. |