|   Domain hiding |   Altered binding specificity |   Motif hiding |   Composite binding site formation |
|   Uncategorised |   Rheostatic |   Allostery |   Avidity-sensing |
|   Physicochemical compatibility |   Pre-translational |   Competition |
| Protein | Start | End | Switch Type | Switch Subtype | Switch Description | Information |
LIG_NRBOX - The nuclear receptor box motif (LXXLL) confers binding to nuclear receptors. | |||||||
| NCOA2_HUMAN | 640 | 646 | Binary | Allostery | Binding of the glucocorticoid ligand to the nuclear Glucocorticoid receptor (NR3C1) makes the binding site for the NRBOX motif of Nuclear receptor coactivator 2 (NCOA2) accessible. | ||
| NCOA2_HUMAN | 689 | 695 | Binary | Allostery | Binding of the glucocorticoid ligand to the nuclear Glucocorticoid receptor (NR3C1) makes the binding site for the NRBOX motif of Nuclear receptor coactivator 2 (NCOA2) accessible. | ||
| NCOA2_HUMAN | 744 | 750 | Binary | Allostery | Binding of the glucocorticoid ligand to the nuclear Glucocorticoid receptor (NR3C1) makes the binding site for the NRBOX motif of Nuclear receptor coactivator 2 (NCOA2) accessible. | ||