Motif | Protein | Start | End | Switch Type | Switch Subtype | Switch description | Information | Evidence |
PI3K-Akt signaling pathway (KEGG - hsa04151) | ||||||||
LIG_SH2_IE | EGFR_HUMAN | 1008 | 1024 | Binary | Physicochemical compatibility | Phosphorylation of Y1016 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to the Tyrosine-protein kinase JAK2 (JAK2) protein. | Inferred |