switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Hide inferred Group Index Colouring Info Filtered: UNIPROT:P10912 (2 hits) x

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Curated inferred

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Information

Evidence

Jak-STAT signaling pathway (KEGG - hsa04630)
LIG_SH2_IIA	GHR_HUMAN	591	600	Binary	Physicochemical compatibility	Phosphorylation of Y595 in the SH2-binding motif of Growth hormone receptor (GHR) induces binding to the Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) protein.	details	Inferred
LIG_SH2_III	GHR_HUMAN	428	444	Binary	Physicochemical compatibility	Phosphorylation of Y436 in the SH2-binding motif of Growth hormone receptor (GHR) induces binding to the Signal transducer and activator of transcription 5B (STAT5B) protein.	details	Inferred