Motif | Protein | Start | End | Switch Type | Switch Subtype | Switch description | Information | Evidence |
ErbB signaling pathway (KEGG - hsa04012) | ||||||||
LIG_PTB_Phospho_1 | ERBB3_HUMAN | 1322 | 1328 | Binary | Physicochemical compatibility | Phosphorylation of Y1328 in the PTB-binding motif of Receptor tyrosine-protein kinase erbB-3 (ERBB3) induces binding to the SHC-transforming protein 1 (SHC1) protein. | Inferred | |
LIG_SH2_GRB2 | ERBB3_HUMAN | 1262 | 1265 | Binary | Physicochemical compatibility | Phosphorylation of Y1262 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-3 (ERBB3) induces binding to Growth factor receptor-bound protein 2 (GRB2). | Curated |