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Group by :Switch typeMotif classProteinEnzymePathway         Hide inferred   Group Index    Colouring Info              Filtered: UNIPROT:P29350 (2 hits) x


x  Coloured by: Pathway evidence source
          Curated          inferred


x  Index
Jak-STAT signaling pathwayNatural killer cell mediated cytotoxicity


MotifProteinStartEndSwitch TypeSwitch SubtypeSwitch descriptionInformationEvidence

Jak-STAT signaling pathway (KEGG - hsa04630)
LIG_SH2_IIA IL4RA_HUMAN706721BinaryPhysicochemical compatibilityPhosphorylation of Y713 in the SH2-binding motif of Interleukin-4 receptor subunit alpha (IL4R) induces binding to the Tyrosine-protein phosphatase non-receptor type 6 (PTPN6) protein.
details
Inferred

Natural killer cell mediated cytotoxicity (KEGG - hsa04650)
LIG_TYR_ITIM KI3L2_HUMAN396401BinaryPhysicochemical compatibilityPhosphorylation of Y398 in the ITIM motif of Killer cell immunoglobulin-like receptor 3DL2 (KIR3DL2) induces binding of Tyrosine-protein phosphatase non-receptor type 6 (PTPN6) via one of its SH2 domains.
details
Inferred
           
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