About Help Definitions Submit Search Analyse Browse Home


Group by :Switch typeMotif classProteinEnzymePathway            Group Index    Colouring Info              Filtered: PFAM:PF00620 (2 hits) x


x  Coloured by switch type.
  Domain hiding  Altered binding specificity  Motif hiding  Composite binding site formation
  Uncategorised  Rheostatic  Allostery  Avidity-sensing
  Physicochemical compatibility  Pre-translational  Competition

x  Index
DCC-interacting protein 13-alpha


MotifStartEndSwitch TypeSwitch SubtypeSwitch DescriptionInformation

DCC-interacting protein 13-alpha - APPL1 -  Homo sapiens
LIG_RhoGAP_OCRL_1403415BinaryPhysicochemical compatibilityPhosphorylation of S403 in the RhoGAP-binding motif of DCC-interacting protein 13-alpha (APPL1), possibly by PKA, inhibits its interaction with Inositol polyphosphate 5-phosphatase OCRL-1 (OCRL).
details
LIG_RhoGAP_OCRL_1403415BinaryPhysicochemical compatibilityPhosphorylation of S410 in the RhoGAP-binding motif of DCC-interacting protein 13-alpha (APPL1) inhibits its interaction with Inositol polyphosphate 5-phosphatase OCRL-1 (OCRL).
details
           
Please send any suggestions/comments to: switches@elm.eu.org