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Group by :Switch typeMotif classProteinEnzymePathway            Group Index    Colouring Info              Filtered: PFAM:PF03271 (3 hits) x
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  Domain hiding  Altered binding specificity  Motif hiding  Composite binding site formation
  Uncategorised  Rheostatic  Allostery  Avidity-sensing
  Physicochemical compatibility  Pre-translational  Competition

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Adenomatous polyposis coli proteinCLIP-associating protein 2Kinesin-like protein KIF2C


MotifStartEndSwitch TypeSwitch SubtypeSwitch DescriptionInformation

Adenomatous polyposis coli protein - APC -  Homo sapiens
LIG_SxIP_EBH_128012811CumulativeRheostaticPhosphorylation of S2789 and S2793 adjacent to the EBH-binding motif of Adenomatous polyposis coli protein (APC), by , respectively, gradually reduces the affinity of its interaction with Microtubule-associated protein RP/EB family member 1 (MAPRE1).
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CLIP-associating protein 2 - CLASP2 -  Homo sapiens
LIG_SxIP_EBH_1515525BinaryPhysicochemical compatibilityPhosphorylation of several serine residues surrounding the EB1-binding motifs of CLIP-associating protein 2 (CLASP2) by Glycogen synthase kinase-3 beta (GSK3B) and Glycogen synthase kinase-3 beta (GSK3B) and Glycogen synthase kinase-3 beta (GSK3B) and Glycogen synthase kinase-3 beta (GSK3B) and Glycogen synthase kinase-3 beta (GSK3B) inhibits its interaction with Microtubule-associated protein RP/EB family member 1 (MAPRE1).
details

Kinesin-like protein KIF2C - KIF2C -  Homo sapiens
LIG_SxIP_EBH_193104BinaryPhysicochemical compatibilityPhosphorylation of S95 and S109 and S111 adjacent to the EB1-binding motif of Kinesin-like protein KIF2C (KIF2C) by Aurora kinase B (AURKB) and Aurora kinase B (AURKB) and Aurora kinase B (AURKB) inhibits its interaction with Microtubule-associated protein RP/EB family member 1 (MAPRE1), thereby inhibiting microtubule tip tracking.
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