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Group by :Switch typeMotif classProteinEnzymePathway            Group Index    Colouring Info              Filtered: UNIPROT:P35568 (4 hits) x
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  Domain hiding  Altered binding specificity  Motif hiding  Composite binding site formation
  Uncategorised  Rheostatic  Allostery  Avidity-sensing
  Physicochemical compatibility  Pre-translational  Competition

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Insulin receptor substrate 1Interleukin-4 receptor subunit alpha


MotifStartEndSwitch TypeSwitch SubtypeSwitch DescriptionInformation

Insulin receptor substrate 1 - IRS1 -  Homo sapiens
DOC_WW_Pin1_4431436BinaryPhysicochemical compatibilityPhosphorylation of S434 in the Pin1-binding motif of Insulin receptor substrate 1 (IRS1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
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LIG_14-3-3_3371376Avidity‑sensingPhosphorylation of two 14-3-3-binding motifs in Insulin receptor substrate 1 (IRS1) induces high-avidity binding to dimeric 14-3-3 protein epsilon (YWHAE).
details
LIG_14-3-3_3638643Avidity‑sensingPhosphorylation of two 14-3-3-binding motifs in Insulin receptor substrate 1 (IRS1) induces high-avidity binding to dimeric 14-3-3 protein epsilon (YWHAE).
details

Interleukin-4 receptor subunit alpha - IL4R -  Homo sapiens
LIG_PTB_Phospho_1491497BinaryPhysicochemical compatibilityPhosphorylation of Y497 in the PTB-binding motif of Interleukin-4 receptor subunit alpha (IL4R) induces binding to the Insulin receptor substrate 1 (IRS1) protein.
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