About Help Definitions Submit Search Analyse Browse Home


Group by :Switch typeMotif classProteinEnzymePathway            Group Index    Colouring Info              Filtered: UNIPROT:Q3UHD6 (2 hits) x


x  Coloured by switch type.
  Domain hiding  Altered binding specificity  Motif hiding  Composite binding site formation
  Uncategorised  Rheostatic  Allostery  Avidity-sensing
  Physicochemical compatibility  Pre-translational  Competition

x  Index
5-hydroxytryptamine receptor 4 (Mus)G protein-activated inward rectifier potassium channel 2 (Mus)


MotifStartEndSwitch TypeSwitch SubtypeSwitch DescriptionInformation

5-hydroxytryptamine receptor 4 - Htr4 -  Mus musculus
LIG_PDZ_Class_1382387BinaryPre‑translationalAlternative splicing removes the PDZ-binding motif of Isoform 5-HT4(A) of 5-hydroxytryptamine receptor 4 (Htr4), abrogating binding to Sorting nexin-27 (Snx27). Snx27 is responsible for targeting of the Isoform 5-HT4(A) of 5-hydroxytryptamine receptor 4 (Htr4) to early endosomes.
details

G protein-activated inward rectifier potassium channel 2 - Kcnj6 -  Mus musculus
LIG_PDZ_Class_1420425BinaryPre‑translationalAlternative splicing removes the PDZ-binding motif of G protein-activated inward rectifier potassium channel 2 (Kcnj6), abrogating binding to Sorting nexin-27 (Snx27).
details
           
Please send any suggestions/comments to: switches@elm.eu.org