Domain hiding |   Altered binding specificity |   Motif hiding |   Composite binding site formation |
  Uncategorised |   Rheostatic |   Allostery |   Avidity-sensing |
  Physicochemical compatibility |   Pre-translational |   Competition |
Motif | Start | End | Switch Type | Switch Subtype | Switch Description | Information |
Proto-oncogene tyrosine-protein kinase receptor Ret - RET -  Homo sapiens | |||||||
LIG_SH2_IIB | 976 | 985 | Binary | Physicochemical compatibility | Phosphorylation of Y981 in the SH2-binding motif of Proto-oncogene tyrosine-protein kinase receptor Ret (RET) induces binding to the SH2B adapter protein 1 (SH2B1) protein. | ||
Tyrosine-protein kinase JAK2 - JAK2 -  Homo sapiens | |||||||
LIG_SH2_IIB | 804 | 823 | Binary | Physicochemical compatibility | Phosphorylation of Y813 in the SH2-binding motif of Tyrosine-protein kinase JAK2 (JAK2) induces binding to the SH2B adapter protein 1 (SH2B1) protein. |