Type: Pre‑assembly Subtype: Composite binding site formation |
The formation of a complex results in the generation of a continuous motif-binding site that spans more than one component of this complex. Neither complex subunit on its own contains a functional binding domain for the motif, and interaction of the motif only occurs in the context of the active, fully assembled complex.
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| IAA7_ARATH | DEG_SCF_TIR1_1 | 82 | 93 | Binding of Auxin-responsive protein IAA7 (IAA7) to Protein TRANSPORT INHIBITOR RESPONSE 1 (TIR1), an F-box substrate recognition subunit of the SCF E3 ubiquitin ligase, depends on binding of the plant hormone auxin to TIR1, as this pre-assembled complex provides a composite binding site for the degron motif in IAA7. Subsequent ubiquitylation of IAA7 by the SCF targets this transcriptional repressor for proteasomal degradation, a pre-requisite for the transcriptional response to auxin. | details |
| IAA17_ARATH | DEG_SCF_TIR1_1 | 82 | 93 | Binding of Auxin-responsive protein IAA17 (IAA17) to Protein TRANSPORT INHIBITOR RESPONSE 1 (TIR1), an F-box substrate recognition subunit of the SCF E3 ubiquitin ligase, depends on binding of the plant hormone auxin to TIR1, as this pre-assembled complex provides a composite binding site for the degron motif in IAA17. Subsequent ubiquitylation of IAA17 by the SCF targets this transcriptional repressor for proteasomal degradation, a pre-requisite for the transcriptional response to auxin. | details |
| IAA1_ARATH | DEG_SCF_TIR1_1 | 55 | 66 | Binding of Auxin-responsive protein IAA1 (IAA1) to Protein TRANSPORT INHIBITOR RESPONSE 1 (TIR1), an F-box substrate recognition subunit of the SCF E3 ubiquitin ligase, depends on binding of the plant hormone auxin to TIR1, as this pre-assembled complex provides a composite binding site for the degron motif in IAA1. Subsequent ubiquitylation of IAA1 by the SCF targets this transcriptional repressor for proteasomal degradation, a pre-requisite for the transcriptional response to auxin. | details |
| IAA28_ARATH | DEG_SCF_TIR1_1 | 48 | 59 | Binding of Auxin-responsive protein IAA28 (IAA28) to Protein TRANSPORT INHIBITOR RESPONSE 1 (TIR1), an F-box substrate recognition subunit of the SCF E3 ubiquitin ligase, depends on binding of the plant hormone auxin to TIR1, as this pre-assembled complex provides a composite binding site for the degron motif in IAA28. Subsequent ubiquitylation of IAA28 by the SCF targets this transcriptional repressor for proteasomal degradation, a pre-requisite for the transcriptional response to auxin. | details |
| IAA12_ARATH | DEG_SCF_TIR1_1 | 69 | 80 | Binding of Auxin-responsive protein IAA12 (IAA12) to Protein TRANSPORT INHIBITOR RESPONSE 1 (TIR1), an F-box substrate recognition subunit of the SCF E3 ubiquitin ligase, depends on binding of the plant hormone auxin to TIR1, as this pre-assembled complex provides a composite binding site for the degron motif in IAA12. Subsequent ubiquitylation of IAA12 by the SCF targets this transcriptional repressor for proteasomal degradation, a pre-requisite for the transcriptional response to auxin. | details |
| IAA3_ARATH | DEG_SCF_TIR1_1 | 64 | 75 | Binding of Auxin-responsive protein IAA3 (IAA3) to Protein TRANSPORT INHIBITOR RESPONSE 1 (TIR1), an F-box substrate recognition subunit of the SCF E3 ubiquitin ligase, depends on binding of the plant hormone auxin to TIR1, as this pre-assembled complex provides a composite binding site for the degron motif in IAA3. Subsequent ubiquitylation of IAA3 by the SCF targets this transcriptional repressor for proteasomal degradation, a pre-requisite for the transcriptional response to auxin. | details |
| TIF6B_ARATH | DEG_SCF_COI1_1 | 303 | 320 | Binding of Protein TIFY 6B (TIFY6B) to Coronatine-insensitive protein 1 (COI1), an F-box substrate recognition subunit of the SCF E3 ubiquitin ligase, depends on binding of the plant hormone jasmonate to COI1, as this pre-assembled complex provides a composite binding site for the degron motif in TIFY6B. Subsequent ubiquitylation of TIFY6B by the SCF targets this transcriptional repressor for proteasomal degradation, a pre-requisite for the transcriptional response to jasmonate. | details |
| TI10A_ARATH | DEG_SCF_COI1_1 | 203 | 220 | Binding of Protein TIFY 10A (TIFY10A) to Coronatine-insensitive protein 1 (COI1), an F-box substrate recognition subunit of the SCF E3 ubiquitin ligase, depends on binding of the plant hormone jasmonate to COI1, as this pre-assembled complex provides a composite binding site for the degron motif in TIFY10A. Subsequent ubiquitylation of TIFY10A by the SCF targets this transcriptional repressor for proteasomal degradation, a pre-requisite for the transcriptional response to jasmonate. | details |
| TIF7_ARATH | DEG_SCF_COI1_1 | 221 | 238 | Binding of Protein TIFY 7 (TIFY7) to Coronatine-insensitive protein 1 (COI1), an F-box substrate recognition subunit of the SCF E3 ubiquitin ligase, depends on binding of the plant hormone jasmonate to COI1, as this pre-assembled complex provides a composite binding site for the degron motif in TIFY7. Subsequent ubiquitylation of TIFY7 by the SCF targets this transcriptional repressor for proteasomal degradation, a pre-requisite for the transcriptional response to jasmonate. | details |
| TI10B_ARATH | DEG_SCF_COI1_1 | 205 | 222 | Binding of Protein TIFY 10B (TIFY10B) to Coronatine-insensitive protein 1 (COI1), an F-box substrate recognition subunit of the SCF E3 ubiquitin ligase, depends on binding of the plant hormone jasmonate to COI1, as this pre-assembled complex provides a composite binding site for the degron motif in TIFY10B. Subsequent ubiquitylation of TIFY10B by the SCF targets this transcriptional repressor for proteasomal degradation, a pre-requisite for the transcriptional response to jasmonate. | details |
| A7XXZ0_SOLLC | DEG_SCF_COI1_1 | 199 | 216 | Binding of LOC100134911 to Coi1, an F-box substrate recognition subunit of the SCF E3 ubiquitin ligase, depends on binding of the plant hormone jasmonate to COI1, as this pre-assembled complex provides a composite binding site for the degron motif in the JAZ protein. Subsequent ubiquitylation of the JAZ protein by the SCF targets this transcriptional repressor for proteasomal degradation, a pre-requisite for the transcriptional response to jasmonate. | details |
| B2XVS2_SOLLC | DEG_SCF_COI1_1 | 251 | 268 | Binding of to Coi1, an F-box substrate recognition subunit of the SCF E3 ubiquitin ligase, depends on binding of the plant hormone jasmonate to COI1, as this pre-assembled complex provides a composite binding site for the degron motif in the JAZ protein. Subsequent ubiquitylation of the JAZ protein by the SCF targets this transcriptional repressor for proteasomal degradation, a pre-requisite for the transcriptional response to jasmonate. | details |
