switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Show inferred Group Index Colouring Info Filtered: PFAM:PF00533 (2 hits) x

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Curated inferred

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Information

Evidence

DNA-dependent protein kinase catalytic subunit - PRKDC - Homo sapiens
LIG_BRCT_MDC1_1	H2AX_HUMAN	139	143	Binary	Physicochemical compatibility	Phosphorylation of S140 in the BRCT-binding motif of Histone H2A.x (H2AFX) induces binding to the Mediator of DNA damage checkpoint protein 1 (MDC1) protein.	details	Curated
Serine-protein kinase ATM - ATM - Homo sapiens
LIG_BRCT_MDC1_1	H2AX_HUMAN	139	143	Binary	Physicochemical compatibility	Phosphorylation of S140 in the BRCT-binding motif of Histone H2A.x (H2AFX) induces binding to the Mediator of DNA damage checkpoint protein 1 (MDC1) protein.	details	Curated