switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Hide inferred Group Index Colouring Info Filtered: UNIPROT:Q13480 (10 hits) x

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Curated inferred

x Index

Epidermal growth factor receptor

Hepatocyte growth factor receptor

Insulin receptor

Motif

Protein

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Information

Evidence

Epidermal growth factor receptor - EGFR - Homo sapiens
LIG_SH2_STAT5	GAB1_HUMAN	472	475	Binary	Physicochemical compatibility	Phosphorylation of Y472 in the SH2-binding motif of GRB2-associated-binding protein 1 (GAB1) induces binding to Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1).	details	Inferred
LIG_SH2_STAT5	GAB1_HUMAN	472	475	Binary	Physicochemical compatibility	Phosphorylation of Y472 in the SH2-binding motif of GRB2-associated-binding protein 1 (GAB1) induces binding to Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1).	details	Inferred
LIG_SH2_STAT5	GAB1_HUMAN	447	450	Binary	Physicochemical compatibility	Phosphorylation of Y447 in the SH2-binding motif of GRB2-associated-binding protein 1 (GAB1) induces binding to Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1).	details	Inferred
LIG_SH2_STAT5	GAB1_HUMAN	447	450	Binary	Physicochemical compatibility	Phosphorylation of Y447 in the SH2-binding motif of GRB2-associated-binding protein 1 (GAB1) induces binding to Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1).	details	Inferred
Hepatocyte growth factor receptor - MET - Homo sapiens
LIG_SH2_STAT5	GAB1_HUMAN	472	475	Binary	Physicochemical compatibility	Phosphorylation of Y472 in the SH2-binding motif of GRB2-associated-binding protein 1 (GAB1) induces binding to Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1).	details	Inferred
LIG_SH2_STAT5	GAB1_HUMAN	447	450	Binary	Physicochemical compatibility	Phosphorylation of Y447 in the SH2-binding motif of GRB2-associated-binding protein 1 (GAB1) induces binding to Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1).	details	Inferred
Insulin receptor - INSR - Homo sapiens
LIG_SH2_STAT5	GAB1_HUMAN	472	475	Binary	Physicochemical compatibility	Phosphorylation of Y472 in the SH2-binding motif of GRB2-associated-binding protein 1 (GAB1) induces binding to Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1).	details	Inferred
LIG_SH2_STAT5	GAB1_HUMAN	472	475	Binary	Physicochemical compatibility	Phosphorylation of Y472 in the SH2-binding motif of GRB2-associated-binding protein 1 (GAB1) induces binding to Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1).	details	Inferred
LIG_SH2_STAT5	GAB1_HUMAN	447	450	Binary	Physicochemical compatibility	Phosphorylation of Y447 in the SH2-binding motif of GRB2-associated-binding protein 1 (GAB1) induces binding to Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1).	details	Inferred
LIG_SH2_STAT5	GAB1_HUMAN	447	450	Binary	Physicochemical compatibility	Phosphorylation of Y447 in the SH2-binding motif of GRB2-associated-binding protein 1 (GAB1) induces binding to Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1).	details	Inferred