switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Show inferred Group Index Colouring Info Filtered: ELM:LIG_SH2_IC (3 hits) x

x Coloured by: Pathway evidence source
Curated inferred

x Index

Motif

Protein

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Information

Evidence

ErbB signaling pathway (KEGG - hsa04012)
LIG_SH2_IC	EGFR_HUMAN	1092	1100	Binary	Physicochemical compatibility	Phosphorylation of Y1092 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.	details	Curated
MAPK signaling pathway (KEGG - hsa04010)
LIG_SH2_IC	EGFR_HUMAN	1092	1100	Binary	Physicochemical compatibility	Phosphorylation of Y1092 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.	details	Curated
PI3K-Akt signaling pathway (KEGG - hsa04151)
LIG_SH2_IC	EGFR_HUMAN	1092	1100	Binary	Physicochemical compatibility	Phosphorylation of Y1092 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.	details	Curated