switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Hide inferred Group Index Colouring Info Filtered: UNIPROT:P09619 (3 hits) x

x Coloured by: Pathway evidence source
Curated inferred

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Motif

Protein

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Information

Evidence

Focal adhesion (KEGG - hsa04510)
LIG_SH2_IIA	PGFRB_HUMAN	751	755	Binary	Physicochemical compatibility	Phosphorylation of Y751 in the SH2-binding motif of Platelet-derived growth factor receptor beta (PDGFRB) induces binding to the Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1) protein.	details	Inferred
PI3K-Akt signaling pathway (KEGG - hsa04151)
LIG_SH2_IIA	PGFRB_HUMAN	751	755	Binary	Physicochemical compatibility	Phosphorylation of Y751 in the SH2-binding motif of Platelet-derived growth factor receptor beta (PDGFRB) induces binding to the Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1) protein.	details	Inferred
Regulation of actin cytoskeleton (KEGG - hsa04810)
LIG_SH2_IIA	PGFRB_HUMAN	751	755	Binary	Physicochemical compatibility	Phosphorylation of Y751 in the SH2-binding motif of Platelet-derived growth factor receptor beta (PDGFRB) induces binding to the Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1) protein.	details	Inferred