Switch #: SWTI000009

Switch type: Uncategorised

Switch subtype: Uncategorised

Description:
Phosphorylation of T156 in AP-2 complex subunit mu (AP2M1) by AP2-associated protein kinase 1 (AAK1) upon clathrin recruitment strengthens the interaction between AP-2 complex subunit mu (AP2M1) and cargo proteins.

Participants:
(1) Lysosomal acid phosphatase (ACP2)
(2) AP-2 complex subunit mu (AP2M1)

(1) Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals.
Ricotta et al. J. Cell Biol. (2002)

Other switches involving participants
AP-2 complex subunit mu (AP2M1) - 15 more (view)

Other switches involving interfaces
TRG_ENDOCYTIC_2 - 21 more (view)
Adaptor complexes medium subunit family - 21 more (view)