About Help Definitions Submit Search Analyse Browse Home


Switch #:
SWTI000017
Switch type:
Binary
Switch subtype:
Physicochemical compatibility

Description:
Phosphorylation of Transcription factor AP-1 (JUN) at S243 primes the protein for phosphorylation at T239 by Glycogen synthase kinase-3 beta (GSK3B).

Participants:
(1) Transcription factor AP-1 (JUN)
(2) Glycogen synthase kinase-3 beta (GSK3B)

Interactions
Context
References

(1) Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity.
Boyle et al. Cell (1991)

See also

Other switches involving participants
Glycogen synthase kinase-3 beta (GSK3B) - 18 more (view)
Transcription factor AP-1 (JUN) - 3 more (view)

Other switches involving interfaces
Protein kinase domain - 35 more (view)
MOD_GSK3_1 - 18 more (view)




Loading visualisation

           
Please send any suggestions/comments to: switches@elm.eu.org