Switch #: SWTI000120

Switch type: Binary

Switch subtype: Physicochemical compatibility

Description:
Phosphorylation of S327 in the BRCT-binding motif of DNA endonuclease RBBP8 (RBBP8) induces binding to the Breast cancer type 1 susceptibility protein (BRCA1) protein.

Participants:
(1) DNA endonuclease RBBP8 (RBBP8)
(2) Breast cancer type 1 susceptibility protein (BRCA1)

(1) Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex.
Varma et al. Biochemistry (2005)

Other switches involving participants
Breast cancer type 1 susceptibility protein (BRCA1) - 6 more (view)

Other switches involving interfaces
LIG_BRCT_BRCA1_1 - 4 more (view)
BRCA1 C Terminus (BRCT) domain - 6 more (view)