Switch #: SWTI000122

Switch type: Binary

Switch subtype: Physicochemical compatibility

Description:
Phosphorylation of S990 in the BRCT-binding motif of Fanconi anemia group J protein (BRIP1) induces binding to the Breast cancer type 1 susceptibility protein (BRCA1) protein.

Participants:
(1) Fanconi anemia group J protein (BRIP1)
(2) Breast cancer type 1 susceptibility protein (BRCA1)

(1) The BRCT domain is a phospho-protein binding domain.
Yu et al. Science (2003)

Other switches involving participants
Breast cancer type 1 susceptibility protein (BRCA1) - 6 more (view)
Fanconi anemia group J protein (BRIP1) - 1 more (view)

Other switches involving interfaces
BRCA1 C Terminus (BRCT) domain - 6 more (view)