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Switch #:
SWTI000145
Switch type:
Binary
Switch subtype:
Physicochemical compatibility

Description:
Phosphorylation of Y496 in the PTB-binding motif of High affinity nerve growth factor receptor (NTRK1) induces binding to the SHC-transforming protein 1 (SHC1) protein.

Participants:
(1) High affinity nerve growth factor receptor (NTRK1)
(2) SHC-transforming protein 1 (SHC1)

Interactions
Context
References

(1) Structure and ligand recognition of the phosphotyrosine binding domain of Shc.
Zhou et al. Nature (1995)

See also

Other switches involving participants
SHC-transforming protein 1 (SHC1) - 15 more (view)
High affinity nerve growth factor receptor (NTRK1) - 2 more (view)

Other switches involving interfaces
LIG_PTB_Phospho_1 - 18 more (view)
Phosphotyrosine interaction domain (PTB/PID) - 14 more (view)




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