Description: Phosphorylation of S210 adjacent to the SH3-binding motif of Isoform Tau-F of Microtubule-associated protein tau (MAPT) inhibits binding to Tyrosine-protein kinase Fyn (Fyn).
Participants: (1) Isoform Tau-F of Microtubule-associated protein tau (MAPT) (2) Tyrosine-protein kinase Fyn (Fyn)
(1) Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cgamma1, Grb2, and Src family kinases.Reynolds et al. J. Biol. Chem. (2008)
Other switches involving interfacesSH3 domain - 7 more (view)LIG_SH3_3 - 5 more (view)
