Description: Phosphorylation of T321 in the PDZ-binding motif of Voltage-dependent calcium channel gamma-2 subunit (Cacng2) by cAMP subfamily prevents binding to the PDZ domain of Disks large homolog 4 (Dlg4), an interaction involved in regulating synaptic targeting of AMPA-selective glutamate receptors.
Participants: (1) Voltage-dependent calcium channel gamma-2 subunit (Cacng2) (2) Disks large homolog 4 (Dlg4)
(1) Phosphorylation of stargazin by protein kinase A regulates its interaction with PSD-95.Choi et al. J. Biol. Chem. (2002)
Other switches involving interfacesPDZ domain (Also known as DHR or GLGF) - 45 more (view)LIG_PDZ_Class_1 - 41 more (view)
