Interaction #1 CTLA4 - AP2M1
(1) TRG_ENDOCYTIC_2 motif (201YVKM204) in Cytotoxic T-lymphocyte protein 4 (CTLA4)
(2) Adaptor complexes medium subunit family (159-435) in AP-2 complex subunit mu (AP2M1)
Effector binding Induction (1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate) of the Cytotoxic T-lymphocyte protein 4 (CTLA4) TRG_ENDOCYTIC_2 motif - AP-2 complex subunit mu (AP2M1) Adaptor complexes medium subunit family interaction
(1) Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2.
Other switches involving participants