Interaction #1 L1CAM - AP2M1
(1) TRG_ENDOCYTIC_2 motif (1176YRSL1179) in Neural cell adhesion molecule L1 (L1CAM)
(2) Adaptor complexes medium subunit family (159-435) in AP-2 complex subunit mu (AP2M1)
Effector binding Induction (1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate) of the Neural cell adhesion molecule L1 (L1CAM) TRG_ENDOCYTIC_2 motif - AP-2 complex subunit mu (AP2M1) Adaptor complexes medium subunit family interaction
ELM curated: cytosol, clathrin-coated endocytic vesicle, plasma membrane
(1) Characterization of the neuron-specific L1-CAM cytoplasmic tail: naturally disordered in solution it exercises different binding modes for different adaptor proteins.
Other switches involving participants