Description: Binding of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to the AP-2 complex alpha, beta and mu subunits exposes a binding site on the AP-2 complex subunit sigma (AP2S1) subunit for recruitment of Envelope glycoprotein (env) via an endocytosis motif.
Participants: (1) Envelope glycoprotein (env) (2) AP-2 complex subunit sigma (AP2S1)
(1) Dileucine and YXXL motifs in the cytoplasmic tail of the bovine leukemia virus transmembrane envelope protein affect protein expression on the cell surface.Novakovic et al. J. Virol. (2004)
Other switches involving participantsEnvelope glycoprotein (env) - 1 more (view)Other switches involving interfacesTRG_LysEnd_APsAcLL_1 - 14 more (view)Clathrin adaptor complex small chain - 15 more (view)
