Description: Participants: Interactions ![]() 1Interaction #1 14-3-3zeta - 14-3-3zeta Interfaces (1) 14-3-3 protein in 14-3-3 protein zeta (14-3-3zeta) (2) 14-3-3 protein (6-239) in 14-3-3 protein zeta (14-3-3zeta) 2Interaction #2 Slob - Interaction #1 14-3-3zeta - 14-3-3zeta Requires Interaction #1 14-3-3zeta - 14-3-3zeta Interfaces (3) LIG_14-3-3_3 motif (51RSNSAI56) in Slowpoke-binding protein (Slob) (4) Interaction #1 14-3-3zeta - 14-3-3zeta Interaction Regulation PTM-dependent Induction (Phosphorylation of S54 on Slowpoke-binding protein (Slob)) of the Slowpoke-binding protein (Slob) LIG_14-3-3_3 motif - 14-3-3 protein interaction Regulatory Enzymes for switch Modifying enzymes for residue: S54: Calcium/calmodulin-dependent protein kinase type II alpha chain (CaMKII) 2Interaction #3 Slob - Interaction #1 14-3-3zeta - 14-3-3zeta Requires Interaction #1 14-3-3zeta - 14-3-3zeta Interfaces (5) LIG_14-3-3_3 motif (76RSASSE81) in Slowpoke-binding protein (Slob) (6) Interaction #1 14-3-3zeta - 14-3-3zeta Interaction Regulation PTM-dependent Induction (Phosphorylation of S79 on Slowpoke-binding protein (Slob)) of the Slowpoke-binding protein (Slob) LIG_14-3-3_3 motif - 14-3-3 protein interaction Regulatory Enzymes for switch Modifying enzymes for residue: S79: Calcium/calmodulin-dependent protein kinase type II alpha chain (CaMKII) Context Switch localisation Curated: cytoplasmic side of plasma membrane ELM curated: nucleus, cytosol, internal side of plasma membrane References (1) A dynamically regulated 14-3-3, Slob, and Slowpoke potassium channel complex in Drosophila presynaptic nerve terminals. See also Other switches involving participants |
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