Switch #: SWTI000435

Switch type: Binary

Switch subtype: Physicochemical compatibility

Description:
Phosphorylation of Y281 in the SH2-binding motif of Signaling lymphocytic activation molecule (SLAMF1) induces binding to the SH2 domain-containing protein 1B (Sh2d1b) protein.

Participants:
(1) Signaling lymphocytic activation molecule (SLAMF1)
(2) SH2 domain-containing protein 1B (Sh2d1b)

(1) Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells.
Morra et al. EMBO J. (2001)

Other switches involving participants
Signaling lymphocytic activation molecule (SLAMF1) - 3 more (view)

Other switches involving interfaces
SH2 domain - 140 more (view)
ELM:LIG_SH2_IB - 13 more (view)