Switch #: SWTI000441

Switch type: Binary

Switch subtype: Physicochemical compatibility

Description:
Phosphorylation of Y246 in the SH2-binding motif of Guanine nucleotide-binding protein subunit beta-2-like 1 (Gnb2l1) induces binding to the Proto-oncogene tyrosine-protein kinase Src (SRC) protein.

Participants:
(1) Guanine nucleotide-binding protein subunit beta-2-like 1 (Gnb2l1)
(2) Proto-oncogene tyrosine-protein kinase Src (SRC)

(1) RACK1 regulates G1/S progression by suppressing Src kinase activity.
Mamidipudi et al. Mol. Cell. Biol. (2004)

Other switches involving participants
Proto-oncogene tyrosine-protein kinase Src (SRC) - 2 more (view)

Other switches involving interfaces
SH2 domain - 140 more (view)
ELM:LIG_SH2_IA - 16 more (view)