Description: Participants: Interactions ![]() 1Interaction #1 rad24 - rad24 Interfaces (1) 14-3-3 protein in DNA damage checkpoint protein rad24 (rad24) (2) 14-3-3 protein (6-241) in DNA damage checkpoint protein rad24 (rad24) 2Interaction #2 mei2 - Interaction #1 rad24 - rad24 Requires Interaction #1 rad24 - rad24 Interfaces (3) LIG_14-3-3_1 motif (435RTESSP440) in Meiosis protein mei2 (mei2) (4) Interaction #1 rad24 - rad24 Interaction Regulation PTM-dependent Induction (Phosphorylation of S438 on Meiosis protein mei2 (mei2)) of the Meiosis protein mei2 (mei2) LIG_14-3-3_1 motif - 14-3-3 protein interaction Regulatory Enzymes for switch Modifying enzymes for residue: S438: Negative regulator of sexual conjugation and meiosis (ran1) 2Interaction #3 mei2 - Interaction #1 rad24 - rad24 Requires Interaction #1 rad24 - rad24 Interfaces (5) LIG_14-3-3_2 motif (523RRSLTVG529) in Meiosis protein mei2 (mei2) (6) Interaction #1 rad24 - rad24 Interaction Regulation PTM-dependent Induction (Phosphorylation of T527 on Meiosis protein mei2 (mei2)) of the Meiosis protein mei2 (mei2) LIG_14-3-3_2 motif - 14-3-3 protein interaction Regulatory Enzymes for switch Modifying enzymes for residue: T527: Negative regulator of sexual conjugation and meiosis (ran1) Context References (1) 14-3-3 protein interferes with the binding of RNA to the phosphorylated form of fission yeast meiotic regulator Mei2p. See also Other switches involving participants |
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