Interaction #1 Ice - th
(1) LIG_BIR_III_4 motif (28DALGS32) in Caspase (Ice)
(2) Inhibitor of Apoptosis domain (47-111) in Apoptosis 1 inhibitor (th)
PTM-dependent Induction (Proteolytic cleavage at D28 on Caspase (Ice)) of the Caspase (Ice) LIG_BIR_III_4 motif - Apoptosis 1 inhibitor (th) Inhibitor of Apoptosis domain interaction
(1) IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms.