Switch #: SWTI000562

Switch type: Binary

Switch subtype: Pre-translational

Description:
Alternative splicing removes the di-arginine ER-retention motif of Glutamate receptor, ionotropic kainate 1 (Grik1), abrogating binding to Coatomer subunit beta (COPB1).

Participants:
(1) Glutamate receptor, ionotropic kainate 1 (Grik1)
(2) Coatomer subunit beta (COPB1)

(1) Cell surface expression of GluR5 kainate receptors is regulated by an endoplasmic reticulum retention signal.
Ren et al. J. Biol. Chem. (2003)

Other switches involving participants
Coatomer subunit beta (COPB1) - 8 more (view)
Glutamate receptor, ionotropic kainate 1 (Grik1) - 1 more (view)

Other switches involving interfaces
Adaptin N terminal region - 8 more (view)