switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Hide inferred Group Index Colouring Info Filtered: PFAM:PF00656 (4 hits) x

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Curated inferred

x Index

Motif

Protein

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Information

Evidence

CK2 subfamily
CLV_C14_caspase-8-10	CASP3_HUMAN	172	175	Binary	Physicochemical compatibility	Phosphorylation of S176 adjacent to the cleavage motif of Caspase-3 (CASP3) by CK2 subfamily prevents cleavage by Caspase-8 (CASP8) and thus activation of Caspase-3 (CASP3).	details	Curated
CLV_C14_Caspase3-7	PTEN_HUMAN	381	385	Binary	Physicochemical compatibility	Phosphorylation of S385 adjacent to the cleavage motif of Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN) by CK2 subfamily prevents cleavage by Caspase-3 (CASP3).	details	Curated
Casein kinase II subunit alpha - CSNK2A1 - Homo sapiens
CLV_C14_Caspase3-7	PTEN_HUMAN	381	385	Binary	Physicochemical compatibility	Phosphorylation of S385 adjacent to the cleavage motif of Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN) by CK2 subfamily prevents cleavage by Caspase-3 (CASP3).	details	Inferred
CLV_C14_Caspase3-7	PTEN_HUMAN	381	385	Binary	Physicochemical compatibility	Phosphorylation of S385 adjacent to the cleavage motif of Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN) by CK2 subfamily prevents cleavage by Caspase-3 (CASP3).	details	Inferred