switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Hide inferred Group Index Colouring Info Filtered: UNIPROT:P19174 (4 hits) x

x Coloured by: Modifier evidence source
Curated inferred

x Index

Motif

Protein

Start

End

Switch Type

Switch Subtype

Switch description

Information

Evidence

Epidermal growth factor receptor - EGFR - Homo sapiens
LIG_SH2_SRC	EGFR_HUMAN	1016	1019	Binary	Physicochemical compatibility	Phosphorylation of Y1016 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1).	details	Inferred
Proto-oncogene tyrosine-protein kinase Src - SRC - Homo sapiens
LIG_SH2_SRC	EGFR_HUMAN	1016	1019	Binary	Physicochemical compatibility	Phosphorylation of Y1016 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1).	details	Inferred
LIG_SH2_SRC	EGFR_HUMAN	1016	1019	Binary	Physicochemical compatibility	Phosphorylation of Y1016 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1).	details	Inferred
Tyrosine-protein kinase ABL1 - ABL1 - Homo sapiens
LIG_SH2_SRC	EGFR_HUMAN	1016	1019	Binary	Physicochemical compatibility	Phosphorylation of Y1016 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1).	details	Inferred