About Help Definitions Submit Search Analyse Browse Home

Group by :Switch typeMotif classProteinEnzymePathway            Group Index    Colouring Info              Filtered: UNIPROT:P19174 (2 hits) x

x  Coloured by switch type.
  Domain hiding  Altered binding specificity  Motif hiding  Composite binding site formation
  Uncategorised  Rheostatic  Allostery  Avidity-sensing
  Physicochemical compatibility  Pre-translational  Competition

x  Index
Epidermal growth factor receptorLinker for activation of T-cells family member 1

MotifStartEndSwitch TypeSwitch SubtypeSwitch DescriptionInformation

Epidermal growth factor receptor - EGFR -  Homo sapiens
LIG_SH2_SRC10161019BinaryPhysicochemical compatibilityPhosphorylation of Y1016 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1).

Linker for activation of T-cells family member 1 - LAT -  Homo sapiens
LIG_SH2_STAT5161164BinaryPhysicochemical compatibilityPhosphorylation of Y161 in the SH2-binding motif of Linker for activation of T-cells family member 1 (LAT) induces binding to the 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) protein.
Please send any suggestions/comments to: switches@elm.eu.org