switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Hide inferred Group Index Colouring Info Filtered: UNIPROT:P25322 (5 hits) x

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Curated inferred

x Index

Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Mus)	Glycogen synthase kinase-3 beta	Glycogen synthase kinase-3 beta (Mus)
PKC subfamily ()

Motif

Protein

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Information

Evidence

PKC subfamily
DOC_CYCLIN_1	AKA12_MOUSE	501	504	Binary	Physicochemical compatibility	Phosphorylation of S507 adjacent to the cyclin-binding motif of A-kinase anchor protein 12 (Akap12) by PKC subfamily blocks binding to the G1/S-specific cyclin-D1 (Ccnd1). As a result, the function of A-kinase anchor protein 12 (Akap12) as a scaffold is inhibited and G1/S-specific cyclin-D1 (Ccnd1) is translocated to the nucleus where it regulates progression of the cell cycle from G1 to S phase.	details	Curated
Dual specificity tyrosine-phosphorylation-regulated kinase 1B - DYRK1B - Mus musculus
DOC_WW_Pin1_4	CCND1_MOUSE	283	288	Binary	Physicochemical compatibility	Phosphorylation of T286 in the Pin1-binding motif of G1/S-specific cyclin-D1 (Ccnd1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein.	details	Inferred
Glycogen synthase kinase-3 beta - GSK3B - Homo sapiens
DOC_WW_Pin1_4	CCND1_MOUSE	283	288	Binary	Physicochemical compatibility	Phosphorylation of T286 in the Pin1-binding motif of G1/S-specific cyclin-D1 (Ccnd1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein.	details	Inferred
DOC_WW_Pin1_4	CCND1_MOUSE	283	288	Binary	Physicochemical compatibility	Phosphorylation of T286 in the Pin1-binding motif of G1/S-specific cyclin-D1 (Ccnd1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein.	details	Inferred
Glycogen synthase kinase-3 beta - GSK3B - Mus musculus
DOC_WW_Pin1_4	CCND1_MOUSE	283	288	Binary	Physicochemical compatibility	Phosphorylation of T286 in the Pin1-binding motif of G1/S-specific cyclin-D1 (Ccnd1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein.	details	Inferred