switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Hide inferred Group Index Colouring Info Filtered: UNIPROT:Q15464 (21 hits) x

x Coloured by: Modifier evidence source
Curated inferred

x Index

Tyrosine-protein kinase Lck	Tyrosine-protein kinase SYK	Tyrosine-protein kinase TXK
Tyrosine-protein kinase ZAP-70

Motif

Protein

Start

End

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Information

Evidence

Tyrosine-protein kinase Lck - LCK - Homo sapiens
LIG_SH2_IIB	VAV_HUMAN	165	180	Binary	Physicochemical compatibility	Phosphorylation of Y174 in the SH2-binding motif of Proto-oncogene vav (VAV1) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
LIG_SH2_IIB	LCP2_HUMAN	105	118	Binary	Physicochemical compatibility	Phosphorylation of Y113 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
LIG_SH2_IIB	LCP2_HUMAN	105	118	Binary	Physicochemical compatibility	Phosphorylation of Y113 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
LIG_SH2_IIB	LCP2_HUMAN	120	133	Binary	Physicochemical compatibility	Phosphorylation of Y128 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
LIG_SH2_IIB	LCP2_HUMAN	120	133	Binary	Physicochemical compatibility	Phosphorylation of Y128 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
LIG_SH2_IIB	LCP2_HUMAN	137	150	Binary	Physicochemical compatibility	Phosphorylation of Y145 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
Tyrosine-protein kinase SYK - SYK - Homo sapiens
LIG_SH2_IIB	LCP2_HUMAN	105	118	Binary	Physicochemical compatibility	Phosphorylation of Y113 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
LIG_SH2_IIB	LCP2_HUMAN	105	118	Binary	Physicochemical compatibility	Phosphorylation of Y113 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
LIG_SH2_IIB	LCP2_HUMAN	120	133	Binary	Physicochemical compatibility	Phosphorylation of Y128 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
LIG_SH2_IIB	LCP2_HUMAN	120	133	Binary	Physicochemical compatibility	Phosphorylation of Y128 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
Tyrosine-protein kinase TXK - TXK - Homo sapiens
LIG_SH2_IIB	LCP2_HUMAN	137	150	Binary	Physicochemical compatibility	Phosphorylation of Y145 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
Tyrosine-protein kinase ZAP-70 - ZAP70 - Homo sapiens
LIG_SH2_IIB	LCP2_HUMAN	105	118	Binary	Physicochemical compatibility	Phosphorylation of Y113 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
LIG_SH2_IIB	LCP2_HUMAN	105	118	Binary	Physicochemical compatibility	Phosphorylation of Y113 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
LIG_SH2_IIB	LCP2_HUMAN	105	118	Binary	Physicochemical compatibility	Phosphorylation of Y113 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
LIG_SH2_IIB	LCP2_HUMAN	105	118	Binary	Physicochemical compatibility	Phosphorylation of Y113 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
LIG_SH2_IIB	LCP2_HUMAN	120	133	Binary	Physicochemical compatibility	Phosphorylation of Y128 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
LIG_SH2_IIB	LCP2_HUMAN	120	133	Binary	Physicochemical compatibility	Phosphorylation of Y128 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
LIG_SH2_IIB	LCP2_HUMAN	120	133	Binary	Physicochemical compatibility	Phosphorylation of Y128 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
LIG_SH2_IIB	LCP2_HUMAN	120	133	Binary	Physicochemical compatibility	Phosphorylation of Y128 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
LIG_SH2_IIB	LCP2_HUMAN	137	150	Binary	Physicochemical compatibility	Phosphorylation of Y145 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred
LIG_SH2_IIB	LCP2_HUMAN	137	150	Binary	Physicochemical compatibility	Phosphorylation of Y145 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.	details	Inferred