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Group by :Switch typeMotif classProteinEnzymePathway         Hide inferred   Group Index    Colouring Info              Filtered: UNIPROT:Q06124 (10 hits) x


x  Coloured by: Modifier evidence source
          Curated          inferred


x  Index
Proto-oncogene tyrosine-protein kinase SrcTyrosine-protein kinase FynTyrosine-protein kinase Lyn


MotifProteinStartEndSwitch TypeSwitch SubtypeSwitch descriptionInformationEvidence

Proto-oncogene tyrosine-protein kinase Src - SRC -  Homo sapiens
LIG_TYR_ITSM OX1R_HUMAN7986Avidity‑sensingOrexin-A induced phosphorylation of the ITSM and ITIM motifs in Orexin receptor type 1 (HCRTR1) allows binding of Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) via its two SH2 domains. Mutation of either tyrosine in the motifs abolishes binding of Tyrosine-protein phosphatase non-receptor type 11 (PTPN11).
details
Inferred
LIG_TYR_ITIM OX1R_HUMAN356361Avidity‑sensingOrexin-A induced phosphorylation of the ITSM and ITIM motifs in Orexin receptor type 1 (HCRTR1) allows binding of Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) via its two SH2 domains. Mutation of either tyrosine in the motifs abolishes binding of Tyrosine-protein phosphatase non-receptor type 11 (PTPN11).
details
Inferred
LIG_TYR_ITSM OX1R_HUMAN7986Avidity‑sensingOrexin-A induced phosphorylation of the ITSM and ITIM motifs in Orexin receptor type 1 (HCRTR1) allows binding of Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) via its two SH2 domains. Mutation of either tyrosine in the motifs abolishes binding of Tyrosine-protein phosphatase non-receptor type 11 (PTPN11).
details
Inferred
LIG_TYR_ITIM OX1R_HUMAN356361Avidity‑sensingOrexin-A induced phosphorylation of the ITSM and ITIM motifs in Orexin receptor type 1 (HCRTR1) allows binding of Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) via its two SH2 domains. Mutation of either tyrosine in the motifs abolishes binding of Tyrosine-protein phosphatase non-receptor type 11 (PTPN11).
details
Inferred

Tyrosine-protein kinase Fyn - FYN -  Homo sapiens
LIG_TYR_ITSM SLAF1_HUMAN277284BinaryPhysicochemical compatibilityPhosphorylation of Y281 in the ITSM motif of Signaling lymphocytic activation molecule (SLAMF1) induces binding of Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) via one of its SH2 domains.
details
Inferred
LIG_TYR_ITSM SLAF1_HUMAN277284BinaryPhysicochemical compatibilityPhosphorylation of Y281 in the ITSM motif of Signaling lymphocytic activation molecule (SLAMF1) induces binding of Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) via one of its SH2 domains.
details
Inferred
LIG_TYR_ITSM SLAF1_HUMAN323330BinaryPhysicochemical compatibilityPhosphorylation of Y327 in the ITSM motif of Signaling lymphocytic activation molecule (SLAMF1) induces binding of Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) via one of its SH2 domains.
details
Inferred
LIG_TYR_ITSM SLAF1_HUMAN323330BinaryPhysicochemical compatibilityPhosphorylation of Y327 in the ITSM motif of Signaling lymphocytic activation molecule (SLAMF1) induces binding of Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) via one of its SH2 domains.
details
Inferred

Tyrosine-protein kinase Lyn - LYN -  Homo sapiens
LIG_TYR_ITSM SLAF1_HUMAN323330BinaryPhysicochemical compatibilityPhosphorylation of Y327 in the ITSM motif of Signaling lymphocytic activation molecule (SLAMF1) induces binding of Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) via one of its SH2 domains.
details
Inferred
LIG_TYR_ITSM SLAF1_HUMAN323330BinaryPhysicochemical compatibilityPhosphorylation of Y327 in the ITSM motif of Signaling lymphocytic activation molecule (SLAMF1) induces binding of Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) via one of its SH2 domains.
details
Inferred
           
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