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Group by :Switch typeMotif classProteinEnzymePathway         Hide inferred   Group Index    Colouring Info              Filtered: ELM:DEG_MDM2_1 (12 hits) x
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5'-AMP-activated protein kinase catalytic subunit alpha-1Casein kinase I isoform alphaCasein kinase I isoform delta
Casein kinase I subfamily ()DNA-dependent protein kinase catalytic subunitDeath-associated protein kinase 1
Dual specificity protein kinase TTKSerine/threonine-protein kinase Chk1Serine/threonine-protein kinase Chk2
Serine/threonine-protein kinase VRK1


MotifProteinStartEndSwitch TypeSwitch SubtypeSwitch descriptionInformationEvidence

5'-AMP-activated protein kinase catalytic subunit alpha-1 - PRKAA1 -  Homo sapiens
DEG_MDM2_1 P53_HUMAN1926BinaryPhysicochemical compatibilityPhosphorylation of Cellular tumor antigen p53 (TP53) on T18 (in vitro by Casein kinase I subfamily, requiring prior phosphorylation of S15) inhibits its binding to E3 ubiquitin-protein ligase Mdm2 (MDM2). In vivo, T18 is phosphorylated in response to DNA damage.
details
Inferred

Casein kinase I subfamily
DEG_MDM2_1 P53_HUMAN1926BinaryPhysicochemical compatibilityPhosphorylation of Cellular tumor antigen p53 (TP53) on T18 (in vitro by Casein kinase I subfamily, requiring prior phosphorylation of S15) inhibits its binding to E3 ubiquitin-protein ligase Mdm2 (MDM2). In vivo, T18 is phosphorylated in response to DNA damage.
details
Curated

Casein kinase I isoform alpha - CSNK1A1 -  Homo sapiens
DEG_MDM2_1 P53_HUMAN1926BinaryPhysicochemical compatibilityPhosphorylation of Cellular tumor antigen p53 (TP53) on T18 (in vitro by Casein kinase I subfamily, requiring prior phosphorylation of S15) inhibits its binding to E3 ubiquitin-protein ligase Mdm2 (MDM2). In vivo, T18 is phosphorylated in response to DNA damage.
details
Inferred

Casein kinase I isoform delta - CSNK1D -  Homo sapiens
DEG_MDM2_1 P53_HUMAN1926BinaryPhysicochemical compatibilityPhosphorylation of Cellular tumor antigen p53 (TP53) on T18 (in vitro by Casein kinase I subfamily, requiring prior phosphorylation of S15) inhibits its binding to E3 ubiquitin-protein ligase Mdm2 (MDM2). In vivo, T18 is phosphorylated in response to DNA damage.
details
Inferred

DNA-dependent protein kinase catalytic subunit - PRKDC -  Homo sapiens
DEG_MDM2_1 P53_HUMAN1926BinaryPhysicochemical compatibilityPhosphorylation of Cellular tumor antigen p53 (TP53) on T18 (in vitro by Casein kinase I subfamily, requiring prior phosphorylation of S15) inhibits its binding to E3 ubiquitin-protein ligase Mdm2 (MDM2). In vivo, T18 is phosphorylated in response to DNA damage.
details
Inferred

Death-associated protein kinase 1 - DAPK1 -  Homo sapiens
DEG_MDM2_1 P53_HUMAN1926BinaryPhysicochemical compatibilityPhosphorylation of Cellular tumor antigen p53 (TP53) on T18 (in vitro by Casein kinase I subfamily, requiring prior phosphorylation of S15) inhibits its binding to E3 ubiquitin-protein ligase Mdm2 (MDM2). In vivo, T18 is phosphorylated in response to DNA damage.
details
Inferred

Dual specificity protein kinase TTK - TTK -  Homo sapiens
DEG_MDM2_1 P53_HUMAN1926BinaryPhysicochemical compatibilityPhosphorylation of Cellular tumor antigen p53 (TP53) on T18 (in vitro by Casein kinase I subfamily, requiring prior phosphorylation of S15) inhibits its binding to E3 ubiquitin-protein ligase Mdm2 (MDM2). In vivo, T18 is phosphorylated in response to DNA damage.
details
Inferred

Serine/threonine-protein kinase Chk1 - CHEK1 -  Homo sapiens
DEG_MDM2_1 P53_HUMAN1926BinaryPhysicochemical compatibilityPhosphorylation of Cellular tumor antigen p53 (TP53) on T18 (in vitro by Casein kinase I subfamily, requiring prior phosphorylation of S15) inhibits its binding to E3 ubiquitin-protein ligase Mdm2 (MDM2). In vivo, T18 is phosphorylated in response to DNA damage.
details
Inferred

Serine/threonine-protein kinase Chk2 - CHEK2 -  Homo sapiens
DEG_MDM2_1 P53_HUMAN1926BinaryPhysicochemical compatibilityPhosphorylation of Cellular tumor antigen p53 (TP53) on T18 (in vitro by Casein kinase I subfamily, requiring prior phosphorylation of S15) inhibits its binding to E3 ubiquitin-protein ligase Mdm2 (MDM2). In vivo, T18 is phosphorylated in response to DNA damage.
details
Inferred

Serine/threonine-protein kinase VRK1 - VRK1 -  Homo sapiens
DEG_MDM2_1 P53_HUMAN1926BinaryPhysicochemical compatibilityPhosphorylation of Cellular tumor antigen p53 (TP53) on T18 (in vitro by Casein kinase I subfamily, requiring prior phosphorylation of S15) inhibits its binding to E3 ubiquitin-protein ligase Mdm2 (MDM2). In vivo, T18 is phosphorylated in response to DNA damage.
details
Inferred
DEG_MDM2_1 P53_HUMAN1926BinaryPhysicochemical compatibilityPhosphorylation of Cellular tumor antigen p53 (TP53) on T18 (in vitro by Casein kinase I subfamily, requiring prior phosphorylation of S15) inhibits its binding to E3 ubiquitin-protein ligase Mdm2 (MDM2). In vivo, T18 is phosphorylated in response to DNA damage.
details
Inferred
DEG_MDM2_1 P53_HUMAN1926BinaryPhysicochemical compatibilityPhosphorylation of Cellular tumor antigen p53 (TP53) on T18 (in vitro by Casein kinase I subfamily, requiring prior phosphorylation of S15) inhibits its binding to E3 ubiquitin-protein ligase Mdm2 (MDM2). In vivo, T18 is phosphorylated in response to DNA damage.
details
Inferred
           
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