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Group by :Switch typeMotif classProteinEnzymePathway            Group Index    Colouring Info              Filtered: ELM:LIG_Actin_RPEL_3 (3 hits) x
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  Domain hiding  Altered binding specificity  Motif hiding  Composite binding site formation
  Uncategorised  Rheostatic  Allostery  Avidity-sensing
  Physicochemical compatibility  Pre-translational  Competition

x  Index
MKL/myocardin-like protein 1 (Mus)Myocardin (Mus)


MotifStartEndSwitch TypeSwitch SubtypeSwitch DescriptionInformation

MKL/myocardin-like protein 1 - Mkl1 -  Mus musculus
LIG_Actin_RPEL_317
61
105		36
80
124		SpecificityMotif hidingHiding of the NLS of MKL/myocardin-like protein 1 (Mkl1) by binding of G-actin to the RPEL motifs of MKL/myocardin-like protein 1 (Mkl1) prevents translocation of this transcription factor to the nucleus.
details

Myocardin - Myocd -  Mus musculus
LIG_Actin_RPEL_32039BinaryPre‑translationalAlternative promoter usage removes the RPEL-binding motif of Myocardin (Myocd), abrogating binding to Actin, alpha skeletal muscle (Acta1). 3 RPEL motifs are found in Myocd. The shortened form lacks 2 RPEL motifs but no definitive comparison of binding to actin has been undertaken between isoforms.
details
LIG_Actin_RPEL_36483BinaryPre‑translationalAlternative promoter usage removes the RPEL-binding motif of Myocardin (Myocd), abrogating binding to Actin, alpha skeletal muscle (Acta1). 3 RPEL motifs are found in Myocd. The shortened form lacks 2 RPEL motifs but no definitive comparison of binding to actin has been undertaken between isoforms.
details
           
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