Domain hiding |   Altered binding specificity |   Motif hiding |   Composite binding site formation |
  Uncategorised |   Rheostatic |   Allostery |   Avidity-sensing |
  Physicochemical compatibility |   Pre-translational |   Competition |
Motif | Start | End | Switch Type | Switch Subtype | Switch Description | Information |
Tyrosine-protein kinase SYK - SYK -  Homo sapiens | |||||||
LIG_SH2_IIC | 315 | 331 | Binary | Physicochemical compatibility | Phosphorylation of Y323 in the SH2-binding motif of Tyrosine-protein kinase SYK (SYK) induces binding to the E3 ubiquitin-protein ligase CBL-B (CBLB) protein. | ||
Tyrosine-protein kinase ZAP-70 - ZAP70 -  Homo sapiens | |||||||
LIG_SH2_IIC | 284 | 300 | Binary | Physicochemical compatibility | Phosphorylation of Y292 in the SH2-binding motif of Tyrosine-protein kinase ZAP-70 (ZAP70) induces binding to the E3 ubiquitin-protein ligase CBL-B (CBLB) protein. |