Interaction #1 - FBXW7
(1) DEG_SCF_FBW7_2 motif (699PPTPPPE705) in Large T antigen
(2) WD domain, G-beta repeat (371-407) and (411-447) and (451-487) and (491-527) and (531-567) and (571-607) and (611-650) in F-box/WD repeat-containing protein 7 (FBXW7)
PTM-dependent Induction (Phosphorylation of T701 on Large T antigen) of the Large T antigen DEG_SCF_FBW7_2 motif - F-box/WD repeat-containing protein 7 (FBXW7) WD domain, G-beta repeat interaction
(1) The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4.
Other switches involving participants