switches
.ELM
About
Help
Definitions
Submit
Search
Analyse
Browse
Home
Group by :
Switch type
Motif class
Protein
Enzyme
Pathway
         
Hide inferred
  
Group Index
  
Colouring Info
             
Filtered:
UNIPROT:Q13291 (10 hits)
x
submit
x
  
Coloured by:
Modifier evidence source
        
 
Curated        
 
inferred
x
  
Index
Tyrosine-protein kinase Fyn
Tyrosine-protein kinase Lyn
Motif
Protein
Start
End
Switch Type
Switch Subtype
Switch description
Information
Evidence
Tyrosine-protein kinase Fyn -
FYN
-  
Homo sapiens
LIG_TYR_ITSM
SLAF1_HUMAN
277
284
Binary
Physicochemical compatibility
Phosphorylation of Y281 in the ITSM motif of
Signaling lymphocytic activation molecule (SLAMF1)
induces binding of
Tyrosine-protein phosphatase non-receptor type 11 (PTPN11)
via one of its SH2 domains.
details
Inferred
LIG_TYR_ITSM
SLAF1_HUMAN
277
284
Binary
Physicochemical compatibility
Phosphorylation of Y281 in the ITSM motif of
Signaling lymphocytic activation molecule (SLAMF1)
induces binding of
Tyrosine-protein phosphatase non-receptor type 11 (PTPN11)
via one of its SH2 domains.
details
Inferred
LIG_TYR_ITSM
SLAF1_HUMAN
323
330
Binary
Physicochemical compatibility
Phosphorylation of Y327 in the ITSM motif of
Signaling lymphocytic activation molecule (SLAMF1)
induces binding of
Tyrosine-protein phosphatase non-receptor type 11 (PTPN11)
via one of its SH2 domains.
details
Inferred
LIG_TYR_ITSM
SLAF1_HUMAN
323
330
Binary
Physicochemical compatibility
Phosphorylation of Y327 in the ITSM motif of
Signaling lymphocytic activation molecule (SLAMF1)
induces binding of
Tyrosine-protein phosphatase non-receptor type 11 (PTPN11)
via one of its SH2 domains.
details
Inferred
LIG_SH2_IB
SLAF1_HUMAN
276
286
Binary
Physicochemical compatibility
Phosphorylation of Y281 in the SH2-binding motif of
Signaling lymphocytic activation molecule (SLAMF1)
induces binding to the
SH2 domain-containing protein 1A (SH2D1A)
protein.
details
Inferred
LIG_SH2_IB
SLAF1_HUMAN
276
286
Binary
Physicochemical compatibility
Phosphorylation of Y281 in the SH2-binding motif of
Signaling lymphocytic activation molecule (SLAMF1)
induces binding to the
SH2 domain-containing protein 1A (SH2D1A)
protein.
details
Inferred
LIG_SH2_IB
SLAF1_HUMAN
273
286
Binary
Physicochemical compatibility
Phosphorylation of Y281 in the SH2-binding motif of
Signaling lymphocytic activation molecule (SLAMF1)
induces binding to the
SH2 domain-containing protein 1B (Sh2d1b)
protein.
details
Inferred
LIG_SH2_IB
SLAF1_HUMAN
273
286
Binary
Physicochemical compatibility
Phosphorylation of Y281 in the SH2-binding motif of
Signaling lymphocytic activation molecule (SLAMF1)
induces binding to the
SH2 domain-containing protein 1B (Sh2d1b)
protein.
details
Inferred
Tyrosine-protein kinase Lyn -
LYN
-  
Homo sapiens
LIG_TYR_ITSM
SLAF1_HUMAN
323
330
Binary
Physicochemical compatibility
Phosphorylation of Y327 in the ITSM motif of
Signaling lymphocytic activation molecule (SLAMF1)
induces binding of
Tyrosine-protein phosphatase non-receptor type 11 (PTPN11)
via one of its SH2 domains.
details
Inferred
LIG_TYR_ITSM
SLAF1_HUMAN
323
330
Binary
Physicochemical compatibility
Phosphorylation of Y327 in the ITSM motif of
Signaling lymphocytic activation molecule (SLAMF1)
induces binding of
Tyrosine-protein phosphatase non-receptor type 11 (PTPN11)
via one of its SH2 domains.
details
Inferred