Domain hiding |   Altered binding specificity |   Motif hiding |   Composite binding site formation |
  Uncategorised |   Rheostatic |   Allostery |   Avidity-sensing |
  Physicochemical compatibility |   Pre-translational |   Competition |
Motif | Start | End | Switch Type | Switch Subtype | Switch Description | Information |
Epidermal growth factor receptor - EGFR -  Homo sapiens | |||||||
LIG_SH2_SRC | 1016 | 1019 | Binary | Physicochemical compatibility | Phosphorylation of Y1016 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1). | ||
Linker for activation of T-cells family member 1 - LAT -  Homo sapiens | |||||||
LIG_SH2_STAT5 | 161 | 164 | Binary | Physicochemical compatibility | Phosphorylation of Y161 in the SH2-binding motif of Linker for activation of T-cells family member 1 (LAT) induces binding to the 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) protein. |