switches.ELM

Group by :Switch type Motif class Protein Enzyme Pathway Hide inferred Group Index Colouring Info Filtered: ELM:LIG_SH3_2 (3 hits) x

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Curated inferred

x Index

Motif

Protein

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Information

Evidence

Axon guidance (KEGG - hsa04360)
LIG_SH3_2	PAK1_HUMAN	13	18	Binary	Physicochemical compatibility	Phosphorylation of S21 adjacent to the SH3-binding motif of Serine/threonine-protein kinase PAK 1 (PAK1) by RAC subfamily inhibits binding to Cytoplasmic protein NCK1 (NCK1), which regulates its localization to focal contacts.	details	Inferred
ErbB signaling pathway (KEGG - hsa04012)
LIG_SH3_2	PAK1_HUMAN	13	18	Binary	Physicochemical compatibility	Phosphorylation of S21 adjacent to the SH3-binding motif of Serine/threonine-protein kinase PAK 1 (PAK1) by RAC subfamily inhibits binding to Cytoplasmic protein NCK1 (NCK1), which regulates its localization to focal contacts.	details	Inferred
T cell receptor signaling pathway (KEGG - hsa04660)
LIG_SH3_2	PAK1_HUMAN	13	18	Binary	Physicochemical compatibility	Phosphorylation of S21 adjacent to the SH3-binding motif of Serine/threonine-protein kinase PAK 1 (PAK1) by RAC subfamily inhibits binding to Cytoplasmic protein NCK1 (NCK1), which regulates its localization to focal contacts.	details	Inferred