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UNIPROT:P24394 (6 hits)
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inferred
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Jak-STAT signaling pathway
PI3K-Akt signaling pathway
Motif
Protein
Start
End
Switch Type
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Information
Evidence
Jak-STAT signaling pathway
(
KEGG - hsa04630
)
LIG_SH2_III
IL4RA_HUMAN
566
585
Binary
Physicochemical compatibility
Phosphorylation of Y575 in the SH2-binding motif of
Interleukin-4 receptor subunit alpha (IL4R)
induces binding to the
Signal transducer and activator of transcription 6 (STAT6)
protein.
details
Inferred
LIG_SH2_III
IL4RA_HUMAN
594
613
Binary
Physicochemical compatibility
Phosphorylation of Y603 in the SH2-binding motif of
Interleukin-4 receptor subunit alpha (IL4R)
induces binding to the
Signal transducer and activator of transcription 6 (STAT6)
protein.
details
Inferred
LIG_SH2_III
IL4RA_HUMAN
622
641
Binary
Physicochemical compatibility
Phosphorylation of Y631 in the SH2-binding motif of
Interleukin-4 receptor subunit alpha (IL4R)
induces binding to the
Signal transducer and activator of transcription 6 (STAT6)
protein.
details
Inferred
LIG_SH2_IIA
IL4RA_HUMAN
706
721
Binary
Physicochemical compatibility
Phosphorylation of Y713 in the SH2-binding motif of
Interleukin-4 receptor subunit alpha (IL4R)
induces binding to the
Tyrosine-protein phosphatase non-receptor type 11 (PTPN11)
protein.
details
Inferred
LIG_SH2_IIA
IL4RA_HUMAN
706
721
Binary
Physicochemical compatibility
Phosphorylation of Y713 in the SH2-binding motif of
Interleukin-4 receptor subunit alpha (IL4R)
induces binding to the
Tyrosine-protein phosphatase non-receptor type 6 (PTPN6)
protein.
details
Inferred
PI3K-Akt signaling pathway
(
KEGG - hsa04151
)
LIG_PTB_Phospho_1
IL4RA_HUMAN
491
497
Binary
Physicochemical compatibility
Phosphorylation of Y497 in the PTB-binding motif of
Interleukin-4 receptor subunit alpha (IL4R)
induces binding to the
Insulin receptor substrate 1 (IRS1)
protein.
details
Inferred
